Особенности формирования микробных биоплёнок на различных субстратах. Возможность изучения биоплёнок на желчных конкрементах

To date, it is an accepted fact that the basic form of existence of bacteria in vivo are associated with the surface of the community – biofilms, which are highly organized, flexible, continuously changing heterogeneous community, consisting of both active functioning cells, because of the dormant forms enclosed in ekzopolimerny matrix, rather than individual planktonic cells. In the latest in domestic and foreign literature while a number of papers covering the microbiological aspect of the problems of gallstone disease, acute and chronic calculous cholecystitis, proving the important role of microorganisms in the development of diseases of the biliary tract and the formation of stones. However, the role of microorganisms in the biofilm development of acute and chronic inflammation, some strains of antibiotic resistance in the presence of stones in the gall bladder remains understudied.