Simultaneous Integrated Boost for Radiation Dose Escalation to the Gross Tumor Volume With Intensity Modulated (Photon) Radiation Therapy or Intensity Modulated Proton Therapy and Concurrent Chemotherapy for Stage II to III Non-Small Cell Lung Cancer: A Phase 1 Study

This phase I portion of a prospective phase I/II study sought to establish the maximum tolerated dose of image-guided, intensity-modulated radiation therapy (IMRT) or proton therapy (IMPT), both with a simultaneous integrated boost (SIB), for patients with stage II-IIIB non-small cell lung cancer (NSCLC) receiving concurrent chemoradiation therapy.