F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through αvβ3 and α5β1 integrin interaction.

Jean-Baptiste Oudart,Matthieu Villemin,Bertrand Brassart,Christèle Sellier,Christine Terryn,Aurélie Dupont-Deshorgue,Jean-Claude Monboisse,François-Xavier Maquart,Laurent Ramont,Sylvie Brassart-Pasco

F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through αvβ3 and α5β1 integrin interaction.

2021

Jean-Baptiste Oudart
Matthieu Villemin
Bertrand Brassart
Christèle Sellier
Christine Terryn
Aurélie Dupont-Deshorgue
Jean-Claude Monboisse
François-Xavier Maquart
Laurent Ramont
Sylvie Brassart-Pasco

We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the ...

Keywords:

Cancer research
Integrin
Melanoma
Cell
Angiogenesis
Cancer
Peptide
Chemistry
α5β1 integrin
Extracellular matrix

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