THE SYNTHESIS AND STRUCTURE OF P(III)-PHOSPHORYLATED 2-AMINOPYRIDINES AND THEIR DERIVATIVES

Abstract A number of the derivatives of 2-aminopyridine and diisopropyl-phosphinous, neopentylene- and pyr-ocatecholphosphorus acids 1−3 and also the diphosphorylated derivative 4 have been obtained. Phosphinite 1 was alkylated by triethyloxoniumtetrafluoroborate with the formation of quasi-phosphonium salt 5 and was protonated by hydrogen chloride at the endocyclic nitrogen atom to form pyridinium salt 6. The structure of all obtained compounds was studied by 1H, 13C, 15N and 31P NMR spectroscopy and it was shown that they exist predominantly in the phosphoaminopyridine form A.