The method of particle labels in a microarray chip detector nucleotide sequence

The present invention discloses a method of marking particles microarray chip detecting nucleotide sequences. One kind of the present invention is disclosed using the micro method of the array chip for detecting a target molecule comprising the steps of: particles, coated with a plurality of functional groups, referred to as the functionalized particles; each target molecules labeled with a modifying group, referred to as modification of the target molecule; the functional groups capable of binding of the modifying group; and a light emitting particles using a functional group-modified so that each of the target molecule can emit light, thereby achieving numerals target molecules. The method of marking particles of the present invention is disclosed for a target molecule can be direct or indirect fluorescent labels, this labeling method not only greatly reduce the cost fluorescence detection, while avoiding the traditional method of fluorescently labeled PCR enrichment process utilizes target nucleic acid molecule the inhibition.