Effect of a Novel Antiallergic Drug, Pemirolast, on Activation of Rat Peritoneal Mast Cells: Inhibition of Exocytotic Response and Membrane Phospholipid Turnover

Hiroshi Fujimiya,Shigeru Nakashima,Hideo Miyata,Yoshinori Nozawa

Effect of a Novel Antiallergic Drug, Pemirolast, on Activation of Rat Peritoneal Mast Cells: Inhibition of Exocytotic Response and Membrane Phospholipid Turnover

1991

Hiroshi Fujimiya
Shigeru Nakashima
Hideo Miyata
Yoshinori Nozawa

The effects of a potent antiallergic drug, pemirolast (TBX), on activation of signal-transducing phospholipase C and A2, were examined in rat peritoneal mast cells. TBX at concentrations be

Keywords:

Immunology
Phospholipid
Mechanism of action
Pemirolast
Arachidonic acid
Signal transduction
Enzyme inhibitor
Biochemistry
Mast cell
Biology
Phospholipase C
Peritoneal cavity

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