The flavonoid casticin enhances TRAIL-induced apoptosis of colon cancer cells through endoplasmic reticulum stress-mediated up-regulation of DR5

Sanyuan Tang,Guangjin Yuan,Zhengyang Yu,Leilan Yin,Hao Jiang

The flavonoid casticin enhances TRAIL-induced apoptosis of colon cancer cells through endoplasmic reticulum stress-mediated up-regulation of DR5

2013

Sanyuan Tang
Guangjin Yuan
Zhengyang Yu
Leilan Yin
Hao Jiang

Objective The aim of this study was to explore the mechanisms by which the flavonoid casticin enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in colon cancer cells.

Keywords:

Casticin
Colorectal cancer
Tumor necrosis factor alpha
Apoptosis
Downregulation and upregulation
Immunology
Flavonoid
Endoplasmic reticulum
Medicine
Surgical oncology
Pathology
Endocrinology
Internal medicine
Cancer research

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