Recovery of renal function and comorbidities in patients with acute kidney injury in the course of severe cardiovascular complications

Introduction: Acute kidney injury (AKI) is a frequent, serious and sometimes unreversable complication in patients with cardiovascular disease. The aim of the study was to evaluate the frequency of recovery renal function and commorbidities in patients with AKI complicating severe cardiovascular diseases. Material and Methods: A retrospective analysis of 246 patients (157 men and 89 women aged 67.9 ± 14.8 years) with AKI in the course of severe cardiovascular diseases, hospitalized in intensive care units and words of nephrological profile in years 2000-2011 were performed. Analysis was based on surveys data collected by regional consultant on the field of nephrology. Based on these data precise information about recovery of renal function was present in 143 documents. Results: In the studied group of 143 patients recovery of renal function was observed in 39 subjects (27.3%). Kidney dysfunction before AKI was observed in 116 patients from the whole study group (47.2%). Such commorbidities like: myocardial infarction, sudden cardiac arrest, diabetes, arterial hypertension, chronic obstructive pulmonary disease or performed operations and grade of biochemical disturbances had no significant influence on recovery of renal function. Complications observed during AKI and anemia negatively influenced on recovery of renal function (p<0.001 and p = 0.007). Patients staying longer at hospital has more frequent recovery of renal function (p = 0.014). Conclusions: Probability of renal function recovery in patients with AKI in the course of severe cardio-vascular complications is low.