Substituent Diversity-Directed Synthesis of Indole Derivatives.
2009
This paper reports a versatile, good-yielding, solution-phase method that is a substituent diversity-directed synthesis of 1H-indoles (6−13, 17−20) and 1-hydroxyindoles (14, 15) starting from commercially available 1,5-difluoro-2,4-dinitrobenzene. The synthetic products possessed the maximum six diversity points.
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