CITOGENÉTICA DEL CÁNCER; ALTERACIONES CROMOSÓMICAS ÚTILES PARA DIAGNÓSTICO OPORTUNO Y PRONÓSTICO EN NEOPLASIAS LINFOPROLIFERATIVAS

This study is about the cytogenetic relevance as an important tool with a lot of clinical applications for diagnosis of diseases, as the cancer. The main objective is to make a critical review about the cancer biology and cytogenetic literatura, to identify chromosomal alterations that are related with high frequency with lymphoproliferative neoplasms, so it can be used as a tool for timely diagnosis, pognosis and follow-up to patient treatment. In the introduction you will find a contextualization and the cancer´s problem, with the description of malignant neoplasms. In the firts two chapters you will find an analysis of the clinical applications of malignant alterations in the cytohenetic studies, there are exposed those neolasias related with primary and secondary chromosomal alterations, classified into three risk groups. Those alterations are summarized in a table. In the last chapters, it corroborates the importance of the cytogenetics alterations as usseful biomarkers for the control of this diseases, with the support of new technologies as FISH and PCR, and there you can find recommendations to advance in the use of cytogenetic to help with this problem.