Novel pyrazole derivative as alk5 inhibitor and uses thereof

The present invention relates to a novel substituted pyrazole derivative, having the effect of inhibiting the serine/threonine kinase activity, targeting the receptor ALK5 of TGF-β. A pharmaceutical composition containing a compound of the present invention as an active ingredient can be usefully used in the treatment and/or prevention of cancer, an autoimmune disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an infectious disease, a pulmonary disease, a cardiovascular disease or a metabolic disease or other diseases associated with a decrease in TGF family signaling activity.