Computerized Cognitive Training: A Review of Mechanisms, Methodological Considerations, and Application to Research in Depression

Computerized cognitive training (CCT) is receiving attention as a promising and widely accessible intervention that is designed to ameliorate the cognitive symptoms commonly seen across multiple clinical populations as well as mood and activities of daily living. The primary purpose of this review is to elucidate the mechanisms of action and response factors of CCT. The secondary purpose is to review and propose the applicability of CCT to individuals with depression who have been shown to experience several cognitive symptoms that often predate, co-occur, and persist even with the resolution of mood symptoms. Design recommendations for future studies are proposed to determine the suitability of CCT as an adjunctive treatment for depression, including use of both active and waitlist control groups and having shorter yet more frequent training protocols.