Abstract 14931: Early Repolarization Defined as J-Point Elevation and Mortality in African Americans: Insights From the Jackson Heart Study

Introduction: Conflicting data exist regarding the association of early repolarization (ER) on electrocardiogram (ECG) and clinical outcomes in African Americans (AA). ST-segment elevation manifested as J-point elevation (JPE), the junction at the end of the QRS complex and beginning of the ST segment, is one of the key features of ER. We examined the association between JPE, as surrogate marker for ER and all-cause mortality in AA in the Jackson Heart Study (JHS). Hypothesis: ER defined as JPE ≥ 0.1 mV in any lead is associated with increased all-cause mortality in AA. Methods: We included JHS participants with ECGs obtained at the baseline visit coding JPE and excluded patients with paced rhythms or QRS duration ≥120 ms. JPE was automatically measured from digitally recorded ECGs at study baseline. We compared the cumulative incidence of 10-year all-cause mortality and 8-year heart failure (HF) hospitalization by presence of ER in any ECG lead at baseline using Kaplan-Meier estimates and multivariable C...