An observational study of RA-ILD at tertiary care hospital in eastern India

Introductions: The spectrum of interstitial lung diseases (ILDs) have mainly been reported from the developed countries; data from developing countries is sparse and conflicting. The aim of this study is to describe the distribution of various RA-ILDs from a tertiary care hospital. Methods: This is an analysis of prospectively collected clinical and demographic data of consecutive subjects with ILDs with special reference to RA-ILD from a single tertiary care medical center. The diagnosis of the specific subtype of ILD was made according to standard criteria for various ILDs.Results: A total of 100 subjects with mean age and standard deviation 52.21 ± 14.41 and 37.0% male and 63.0% female were enrolled during the study period (March 2017 to December 2018). Cough was the most common symptoms 100.0% followed by 28.0%, shortness of breath (SOB) 98.0%, Wheezing 32.0%, Chest Pan (Pleuritic) 41.0% subjects had a restrictive defect on spirometry It was found that 61% subjects had pallor, 40% subjects had clubbing, 42% subjects had edema, 65% subjects had arthalgia (S/L), 37% subjects had skin manifestations and 14% subjects had mucosal involment. Total in16 no. of RA-ILD cases (9) male (7) female having UIP pattern n-11 & NSIP pattern in n-5 cases.Conclusion: RA-ILD among the CTD-ILDs was the most common ILDs seen at a tertiary center in earthern India similar to the spectrum reported from developed countries. More studies are required from developing countries to ascertain the spectrum of ILDs in different geographic locales.