Human Adipose Stromal Cells Increase Survival and Mesenteric Perfusion Following Intestinal Ischemia and Reperfusion Injury

Amanda R. Jensen,Dominique L. Doster,E. Bailey Hunsberger,Morenci M. Manning,Samantha M. Stokes,Daria Barwinska,Keith L. March,Mervin C. Yoder,Troy A. Markel

Human Adipose Stromal Cells Increase Survival and Mesenteric Perfusion Following Intestinal Ischemia and Reperfusion Injury

2016

Amanda R. Jensen
Dominique L. Doster
E. Bailey Hunsberger
Morenci M. Manning
Samantha M. Stokes
Daria Barwinska
Keith L. March
Mervin C. Yoder
Troy A. Markel

ABSTRACTObjective:Intestinal ischemia can quickly escalate to bowel necrosis and perforation. Transplantation of stem cells presents a novel treatment modality for this problem. We hypothesized that: human adipose-derived stromal cells (hASCs) would increase survival and mesenteric perfusion to a gr

Keywords:

Pathology
Stromal cell
Inflammation
Adipose tissue
Intestinal ischemia
Reperfusion injury
Perfusion
Mesenteric arteries
Medicine

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