Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency

Yaqian Duan,Ram Prasad,Dongni Feng,Eleni Beli,Sergio Li Calzi,Ana Leda F. Longhini,Regina Lamendella,Jason L. Floyd,Mariana Dupont,Sunil K. Noothi,Gopalkrishna Sreejit,Baskaran Athmanathan,Justin P. Wright,Amanda R. Jensen,Gavin Y. Oudit,Troy A. Markel,Prabhakara R. Nagareddy,Alexander G. Obukhov,Maria B. Grant

Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency

2019

Yaqian Duan
Ram Prasad
Dongni Feng
Eleni Beli
Sergio Li Calzi
Ana Leda F. Longhini
Regina Lamendella
Jason L. Floyd
Mariana Dupont
Sunil K. Noothi
Gopalkrishna Sreejit
Baskaran Athmanathan
Justin P. Wright
Amanda R. Jensen
Gavin Y. Oudit
Troy A. Markel
Prabhakara R. Nagareddy
Alexander G. Obukhov
Maria B. Grant

Rationale: There is incomplete knowledge of the impact of bone marrow cells on the gut microbiome and gut barrier function. Objective: We postulated that diabetes mellitus and systemic ACE2 (angiot...

Keywords:

Immunology
gut microbiome
incomplete knowledge
gut barrier
Medicine
Bone marrow
functional integrity
Diabetes mellitus

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