Sleep modulation of epileptic activity in mesial and neocortical temporal lobe epilepsy: A study with depth and subdural electrodes ☆

Abstract This study characterizes the spatial–temporal distribution of epileptic activity in mesial and neocortical temporal lobe epilepsy (TLE) assessed by subdural and depth electrodes during sleep. We determined in 13 patients the frequency, lateralization, and localization of interictal epileptic discharges (IEDs). As compared to the waking state, IEDs increased in light sleep (196%, p