Urinary clusterin—a novel urinary biomarker associated with pediatric lupus renal histopathologic features and renal survival

Background Lupus nephritis (LN) is a major risk factor for systemic lupus erythematous (SLE)-related morbidity and mortality. With the aim of bypassing renal biopsy, we analyzed urinary biomarkers for their ability to predict renal histopathologic features and end-stage kidney disease (ESKD).