Effects of Turnera ulmifolia (Linn.) Leaves on Blood Glucose Level in Normal and Alloxan-Induced Diabetic Rats

The methanolic extract of leaves of Turnera ulmifolia L was evaluated for its effect on blood glucose in alloxan-induced diabetic and euglycemic rats. The extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. Glibenclamide (10 mg/kg, p.o.) was used as standard for control group. In euglycemic rat, extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. Extract at 400 mg/kg and glibenclamide significantly reduced blood glucose level in normal and alloxan-induced diabetic rats and raised the liver glycogen content significantly. This indicates that the leaves extract of Turnera ulmifolia L posses anti-hyperglycemic activity.