AL ASSAY FOR DNA METHYLATION BAS ELECTRODE AND METHYL BINDING DO

This paper presents an electroche method of DNA methylation using a 3D gold electrode and a methyl binding do (MBD 1). For sensitive detection of DNA 3D nanostructured gold electrode is d combination of an electrochemical depositi conventional photolithography process. It larger active surface area than that of electrode. In addition, the methyltransfe measured by the label-free based di voltammetry (DPV) response by the intera to the methylated site. The proposed dete able to detect the methyltransferase activity U/ml.