New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling
2016
Photodynamic therapy (PDT) has been theoretically investigated using a Monte Carlo radiation transfer (MCRT)
model. By including complex three dimensional (3D) tumour models a more appropriate representation of the
treatment was achieved. The 3D clustered tumour model was compared to a smooth model, resulting in a
significantly deeper penetration associated with the clustered model. The results from the work presented here
indicates that light might penetrate deeper than suggested by 2D or simple layered models.
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