A feasibility and safety study of vaccination with Poly-ICLC and peptide-pulsed dendritic cells in patients with advanced pancreatic adenocarcinoma.

Shikhar Mehrotra,Carolyn D. Britten,Steve Chin,Mohamed L. Salem,Colleen A. Cloud,Michelle H. Nelson,Chrystal M. Paulos,Elizabeth Garrett-Mayer,Mark P. Rubinstein,Zihai Li,David J. Cole

A feasibility and safety study of vaccination with Poly-ICLC and peptide-pulsed dendritic cells in patients with advanced pancreatic adenocarcinoma.

2016

Shikhar Mehrotra
Carolyn D. Britten
Steve Chin
Mohamed L. Salem
Colleen A. Cloud
Michelle H. Nelson
Chrystal M. Paulos
Elizabeth Garrett-Mayer
Mark P. Rubinstein
Zihai Li
David J. Cole

e14579Background: Dendritic cells (DCs) shape the quantity and quality of anti-tumor immunity in patients with cancer. We hypothesized that DC-based immunotherapy, in conjunction with a novel long-...

Keywords:

Poly ICLC
Cancer research
Vaccination
Pathology
Oncology
Peptide
Adenocarcinoma
Internal medicine
Medicine
Immunotherapy
Cancer
Immunity
in patient

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