EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF ERVATAMIA HEYNEANA ROOTS

The analgesic activity was assessed by using acetic acid induced writhing in mice and tail-flick method using rats. A dose dependent analgesic activity was observed with diethyl ether extract of the roots of Ervatamia heyneana. A significant analgesic activity was observed at a dose of 100, 200 and 400mg/kg body weight. On the other hand, the anti-inflammatory activity was assessed by carrageenan induced paw oedema in rats. A dose dependent anti-inflammatory activity was observed with diethyl ether extract of the roots of E. heyneana. A significant anti-inflammatory activity was observed at a dose of 100, 200 and 400mg/kg body weight.