Differential approach to administration of cosaar

: Effects of cosaar (MSD) on central hemodynamics and microcirculation were studied in 20 patients with arterial hypertension under acute pharmacological test and on the treatment week 2, 6 and 8. Two variants of hemodynamic response were registered: hypokinetic and hyperkinetic. Unidirectional hemodynamic changes occurred both in short- and long-term therapy. This allows to use the short course for differential choice of patients for cosaar therapy. The best effect of cosaar is expected in patients with a hyperkinetic variant of the hemodynamic response under the short treatment course.