The action of palytoxin on erythrocytes and resealed ghosts. Formation of small, nonselective pores linked with Na+, K+-ATPase.

Palytoxin increases the permeability of human erythrocytes and their resealed ghosts. To elucidate its mode of action the activation by ATP and Ca2+, the inhibition by ouabain, and the changes in permselectivity have been studied: