A 70% hepatectomy in the rat using a microsurgical technique.

Abstract An experimental model of 70% hepatectomy in the rat using a microsurgical technique is described. An operative microscope (Carl Zeiss 10x2) dissection made it possible to identify the hilar anatomical variations and then to avoid unexpected damage to the arterio-portal and biliary branches belonging to the remaining hepatic parenchyma. The use of this microsurgical technique allows for a more homogenous experimental model because it avoids the functional impairment of the remaining liver.