Curcumin salicylic acid monoester and synthesis method thereof and application curcumin salicylic acid monoester in anti-tumor and anti-inflammatory aspects

The invention relates to curcumin salicylic acid monoester shown as a formula (I). A synthesis method of the curcumin salicylic acid monoester comprises the following steps of: dissolving curcumin in absolute methylene dichloride; adding salicylic acid and a catalytic amount of DMAP (N, N-4-dimethyl aminopyridine); slowly dropwise adding methylene dichloride in which a dehydrant DCC (dicyclohexylcarbodiimide) or EDC.HCl [1-ethyl-(3-dimethyl amino propyl) carbonyl diimine hydrochloride] to perform esterification reaction; and performing separation and purification on a product through column chromatography. The curcumin salicylic acid monoester has an inhibition effect on leukemia, lymphoma, gastric cancer, cancer of colon, liver cancer, pancreatic cancer, breast carcinoma, nasopharyngeal carcinoma, cervical cancer, melanoma and multiple myeloma cells; the anti-tumor effect is superior to that of curcumin; and the toxicity of a medicament is not increased while the anti-tumor effect is improved. The curcumin salicylic acid monoester has an obvious inhibition effect on acute and chronic inflammation models.