The effects of the aqueous extract of celery (Apium graveolens ) on hematological parameters and the level of serum testosterone hormone in male rats.

The Effects of Aqueous Extract of Celery (Apium Graveolens) on Hematological Parameters and on the Level of Serum Testosterone in Male Rat Ameneh Hardani1*, Esrafil Mansouri2, Ashraf Zargar3, Hamid Reza Afzal Zadeh4 Abstract Background and Objectives: In Iran, traditionally, celery is used to treat of various diseases such as peptic ulcer. The aim of this study was to investigate the effects of the aqueous extract of celery (Apium graveolens) on hematological parameters and testosterone in male rats. Subjects and Methods: Twenty four adult rats were divided into 3 groups: Control and two experimental groups, which received the aqueous extract of celery at doses 100 and 200mg/Kg for 30 consecutive days. At the end of this period, all the animals were killed and blood samples were collected and the hematologic factors (hemoglobin, RBC, MCH and WBC) and serum testosterone levels were measured. The results were analysed by one-way ANOVA test. Results: Aqueous extract of celery, without affecting body weight, increased hemoglobin, MCH, WBC and as well as a significant increase of serum testosterone. Conclusions: The aqueous extract of celery can increase testosterone level and some blood parameters in rat. ►Please cite this paper as: Hardani A, Mansouri E, Zargar A, Afzal Zadeh HR The Effects of Aqueous Extract of Celery (Apium Graveolens) on Hematological Parameters and on the Level of Serum Testosterone in Male Rat.