Long-term Variability of Oscillatory Impedance in Stable Obstructive Airways Disease.

Respiratory oscillometry (or Forced Oscillation Technique (FOT)), measures the mechanical properties of the respiratory system by superimposing oscillatory pressure waves at the mouth during quiet tidal breathing. Parameters include respiratory system resistance (Rrs), a measure of airway calibre; and reactance (Xrs), representing the elastic and inertive properties which are sensitive to airway closure [1]. FOT is increasingly being used for clinical monitoring of airways disease, which complements spirometric function [2]. Footnotes This manuscript has recently been accepted for publication in the European Respiratory Journal . It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article. Conflict of interest: Dr. Rutting has nothing to disclose. Conflict of interest: Miss Badal has nothing to disclose. Conflict of interest: Mr Wallis has nothing to disclose. Conflict of interest: Mrs. Schoeffel has nothing to disclose. Conflict of interest: Dr. Roche has nothing to disclose. Conflict of interest: Dr. Cottee has nothing to disclose. Conflict of interest: Dr. Chapman has nothing to disclose. Conflict of interest: Dr. Greenwood has nothing to disclose. Conflict of interest: Dr. Farah has nothing to disclose. Conflict of interest: Dr. King reports grants, personal fees and non-financial support from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Menarini, MundiPharma and Novartis; and 2) unrestricted research grants from: NHMRC, Boehringer Ingelheim, CycloPharma, GlaxoSmithKline, Menarini, MundiPharma, Philanthropic individuals and societies. , non-financial support and other from Restech, Italy during the conduct of the study. Conflict of interest: Dr. Thamrin has a patent WO 2006130922 A1 issued which is broadly relevant to the work. In addition, Dr. Thamrin has intellectual property arrangements with Thorasys Medical Systems and Restech srl relating to research collaborations, but does not have any financial relationships with either company.