MYOCARDIAL ISCHEMIA AND INFARCTION ELEVATION OF PLASMA COPEPTIN IN ACUTE MYOCARDIAL INFARCTION IN PIGS IS RELATED TO CHANGES IN MEAN ARTERIAL BLOOD PRESSURE BUT NOT TO MYOCARDIAL ISCHEMIA

Highest copeptin levels were measured 30 minutes after coronary occlusion. There was a strong correlation between mean arterial pressure (MAP) and copeptin kinetics. Animals with high copeptin values showed a signiicant drop of MAP in consequence of AMI, whereas in animals with stable MAP after infarction levels did not raise (Fig.1b). Infarction size, heart rate and urine volume did not show any correlation with the extent of copeptin levels.