Potentiating Immune System by Hyperthermia

Hyperthermia enhances the host immune responses against cancer through several mechanisms; activating immune cells (e.g., natural killer cells, dendritic cells, and cytotoxic T lymphocytes), canceling immune suppression, altering cell-surface molecules on cancer cells, and modifying adhesion molecules on immune cells and endothelial cells. This chapter discusses the positive effects of hyperthermia on the host immune system.