Оптимизация поверхности титановых дентальных имплантатов сплава grade 5 барьерным стеклокерамическим покрытием

Pateks — the technology of applying a biocompatible glass-ceramic coating based on silicon, carbon and nitrogen on dental implants by PECVD is developed by research and production company Plasmacentre and Pavlov University (St. Petersburg, Russia). Purpose of the research — to evaluate the success of optimization of the surface of doped titanium endosseous dental implants which may be achieved with our glass-ceramic barrier coating technology using physicochemical, cytological, spectrophotometric and biological researches. The main task is to carry out a comparative assessment of the studies’ results between dental implants with and without Pateks glass-ceramic coating (doped with titanium alloy). Materials and methods. Titanium implants (grade 5) from BioMed were used in this research. Some of them were coated with Pateks according to our technology. A human lung fibroblast cells culture was used for the cytological study. Spectrophotometric studies were carried out on atomic absorption spectrophotometer and a atomic absorption spectrometer KVANT-Z.ETA (Russia). Biological studies were carried out on 6 Chinchilla rabbits. Findings. Pateks-coated implants demonstrate advantage in comparison with non-coated ones in certain physicochemical parameters such as decrease of defects’ area in the initial surface of titanium implants which is formed on the previous stages of surface shaping and processing, providing higher surface hydrophilicity, increasing of dielectric characteristics and higher pH value. Pateks coating is safe for fibroblast monolayers and does not inhibit respiratory processes in them. Applying of Pateks glass-ceramic coating with a thickness of 0.5 μm reduces the content of aluminum and vanadium ions in the model medium by almost 2 times and provides a barrier that helps to reduce the negative biological effect of these ions on peri-implant tissues. There is a reduction in the osseointegration time of experimental coated titanium implants in a study on rabbits.