Morbidity and Function Loss After Resection of Malignant Peripheral Nerve Sheath Tumors

BACKGROUND Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas. Their resection may lead to serious morbidity. Incidence of postoperative motor and sensory deficits is unknown, and reconstruction aimed at restoring such deficits is infrequently carried out. OBJECTIVE To identify the incidence and risk factors of postoperative morbidity in MPNST as well as the use and outcomes of functional reconstructions in these patients. METHODS Postoperative function and treatment of MPNSTs diagnosed from 1988 to 2019 in 10 cancer centers was obtained. Two models were constructed evaluating factors independently associated with postoperative motor (

Keywords:

• Buttocks
• Surgery
• Sensation
• Sensory loss
• Multimodal therapy
• Soft tissue
• Plexus
• Neurofibromatosis
• Cancer
• Medicine

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