High-performance Antiviral Nano-Systems as a shield to inhibit viral infections: SARS-CoV-2 as Model Case Study

Despite significant accomplishments in developing rapid sensing systems and nano-therapeutics, the recent COVID-19 pandemic is not under the control successfully because severe acute respiratory virus (SARS-CoV-2) transmits easily human-to-human and causes life-threatening respiratory disorder. Thus, it emerged particularly important to avoid this transmission through precautions and keeps premises hygiene using high-performance anti-viral nanomaterials to trap and eradicate SARS-CoV-2. Such an antiviral nano-system has successfully demonstrated useful significant contribution in COVID-19 pandemic/endemic management. However, their projection with potential sustainable prospects still requires a considerable attention. With this aim, the presented review highlights various severe life-threatening viral infections and the role of multi-functional anti-viral nanostructures investigated as an efficient precative shielding agent against viral infection progression. The salient features of such various nanostructures, antiviral mechanisms, and high impact multi-dimensional roles are systematically discussed in this report. Additionally, the challenges associated with the projection of alternative approaches also support the demand of the selected scientific topic. The outcomes of this report will certainly be useful to motivate scholars of various expertise who are planning future research in the field of investigating sustainable and affordable high-performance nano-system of desired antiviral performance to manage not only COVID-19 infection but other targeted viral infection as well.