GW28-e1225 The Cardioprotective Effects of Trimetazidine in Dilated Cardiomyopathy patients with left bundle branch block

Left bundle branch block (LBBB) patients with dilated cardiomyopathy (DCM) remain highly symptomatic with a poor prognosis. As failure progresses, mitochondrial oxidative metabolism is reduced and glycolysis is increased with the down regulation of glucose and fatty acid oxidation. Trimetazidine may