Correlación cito-histológica de las lesiones premalignas y malignas de cuello uterino

2010 
El control de la calidad es obligatorio para cualquier programa. Es importante en el diagnostico de lesiones de cuello uterino puesto que el cancer cervical es la segunda causa de mortalidad en la mujer. Objetivos: Determinar la correlacion cito-histologica de las lesiones premalignas y malignas de cuello uterino. Hospital Clinico Quirurgico "Abel Santamaria" en el periodo 2004-2007 Diseno: Se realizo un estudio de validacion externa de la citologia organica del cuello uterino mediante un diseno observacional, descriptivo y transversal. Sujetos y metodo. Universo: 7174 mujeres con biopsia del cuello uterino, de las cuales 3240 provenian del Programa de Deteccion Precoz del Cancer Cervico-Uterino (PDPCCU). Se determino la edad, correspondencia diagnostica entre citologia y biopsia y el rendimiento de la citologia organica segun tipo de lesion. Se uso la estadistica descriptiva para resumir las variables categoricas y cuantitativas continuas. Se calculo la sensibilidad y la especificidad de los diagnosticos. Resultados. Se produjo un aumento progresivo de las biopsias de cuello realizadas, con un incremento significativo de los casos del PDPCCU. Predomino el diagnostico de lesiones premalignas; las mas frecuentes fueron las NIC I. La correlacion cito-histologica y la sensibilidad aumentaron con la severidad de las lesiones. La especificidad se mantuvo constante para todas las lesiones. Conclusion. Se comprobo que la calidad se mantiene entre los estandares internacionales. Quality control is compulsory for any programs, being of a great importance the diagnosis of the lesions in the cervix, cervical cancer is the second cause of death in women. Objectives: To determine the cyto-histological correlation of the pre-malignant and malignant lesions of the cervix. This research paper was carried out at "Abel Santamaria Cuadrado" University Hospital during 2004-2007. Design: An external validation study was conducted on the organic cytology of the cervix by means of an observation, descriptive and cross-sectional design. Subjects and method: Universe: 7174 women with cervix biopsy specimen, out of them 3240 came from the "Programa de Deteccion Precoz del Cancer Cervico-Uterino (PDPCCU)" (Program for the Early Detection of Cervical Cancer). Age, diagnostic correspondence with the cytology and the biopsy; as well as the yield of the organic cytology according to the type of lesion; using Descriptive Statistics to sum up the categorical and continuing quantitative variables. Sensitivity and specificity of the diagnosis was calculated. Results: A progressive increase in the cervix biopsies performed and a significant increment of the cases recorded in the Program for the Early Detection of Cervical Cancer were observed; diagnosis of the premalignant lesions prevailed and the most frequent were those identified of Cervical Intraepithelial Neoplasia (CIN-1). Cyto-histological correlation and sensitivity increased with the severity of the lesions. Conclusion: It was proved that the quality control maintains the international standards.
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