RESISTENCIA BACTERIANA EN UROCULTIVOS DE UNA POBLACIÓN DE EMBARAZADAS DE CONTROL PRENATAL EN BOGOTÁ JUNIO 2013 – JUNIO 2015

Urinary tract infection (UTI), specifically asymptomatic bacteriuria, affects 2% to 7% of pregnancies; without treatment, it evolves into pyelonephritis, increases the probability of preterm birth, low birth weight and preeclampsia. Detection and treatment of UTI is a priority. Knowing the antibiotic sensitivity of different pathogens allows us to review treatment strategies and reduce adverse perinatal outcomes. Objective: To determine the resistance profile of the main pathogens isolated in urine cultures of pregnant patients who attended prenatal care in Clinica Colsanitas. Materials and Methods: An observational study was performed with pregnant patients who attended prenatal care. All urine culture results were taken from the pregnant patients and urine cultures suggestive of contamination were excluded. The isolated pathogens and the sensitivity to the different antibiotics were analyzed. Results: Out of 14054 urine samples, 1177 were positive. The main isolated pathogen was Escherichia coli with a prevalence of 71.4%, followed in frequency by Enterococcus faecalis, Proteus mirabilis and Klebsiella pneumoniae. The resistance of Escherichia coli to ampicillin was 37.3%, trimethoprim sulfamethoxazole 23.3%, cefalotin 11.1%. The sensitivity to fosfomycin was 98%. In general, the most frequently isolated pathogens showed low rates of beta-lactamase expression. Conclusions: E. coli was the most frequent pathogen. The high resistance to ampicillin contraindicates its empirical use. The use of other antibiotics such as cephalexin or nitrofurantoin is adequate. Fosfomycin may be an option when it is not possible to use previously described.