N,n'-substituted 3,7-diazabicyclo[3,3,1]nonanes with pharmacological effect, pharmacological compositions on their base, and application method

FIELD: chemistry. SUBSTANCE: invention concerns new N,N'-substituted 3,7-diazabicyclo[3.3.1]nonanes of the general formula 1: (HY), where HY is hereinafter a pharmacologically acceptable acid; E is , R 1 is H, low-grade alkyl, C 1 -C 10 alkoxy; R 2 is generally represented by the general formulae (1.1a) , (1.2a) , (1.3a) , (1.4a) , where L is CHR 11 , ; R 11 is H, NH 2 ; R 15 is H, low-grade alkyl, C 1 -C 10 alkoxy; R 19 , R 19 ', R 20 and R 20 ' can be equal or different, and each is independently H, low-grade alkyl, C 1 - C 10 alkoxy; R 24 and R 25 can be equal or different, and each is independently H, low-grade alkyl, C 1 - C 10 alkoxy; R 3 and R 3 ' can be equal or different, and each is independently H, low-grade alkyl, C 1 - C 10 alkoxy; R 4 and R 4 ' can be equal or different, and each is independently H, low-grade alkyl, C 1 - C 10 alkoxy; X is a group of the general formula: (CH 2 ) m -Z, where m=0, while Z is acetyl, or X is a valence link. Compounds I are capable of AMPA receptor activity modulation and hence can be applied in pharmaceutical compositions. EFFECT: obtaining compound capable of AMPA receptor activity modulation. 12 cl, 2 dgw, 2 tbl, 11 ex