5-hydroxy-2'-nitroaurone or 5-hydroxy-4'-nitroaurone derivatives and application thereof

The invention discloses a 5-hydroxy-2'-nitroaurone or 5-hydroxy-4'-nitroaurone derivatives and application thereof, wherein the derivatives are a compound represented as the formula (I), an isomer or a pharmaceutically acceptable salt thereof. The compound is excellent in inhibition activity on endothelial cells and tumor cells comprising A549, Bel-74021 and MCF-7, and is excellent in inhibition effects on migration and invasion of the tumor cell A549.