Research on the Anti-diabetic Effects of Shi-liang Tea Extract

The effect of shi-liang tea extract,a major Anhua deep-black tea,on blood glucose in db/db dia-betic mice,was studied.The three different dose of water extract shi-liang tea(100,200 or 400 mg/kg) were orally treated per day in 6～8 week-old db/db diabetic mice for 28 days.The level of fast blood glucose(FBG) was determined per week in the experiment period,and glucose tolerance and insulin level were determined at the end of the experiment.Treatment with shi-liang tea(400 mg/kg) for 28 days could markedly decrease FBG and insulin level in db/db diabetic mice.This treatment also improved the glucose tolerance and in-crease insulin release in glucose load experiment in db/db diabetic mice.The water extract of shi-liang tea exert a strong lowering-glucose effect and its effect may be related to increasing sensibility of tissues to insulin.