Chronic Kidney Disease Epidemiology Collaboration Equation Accuracy in Predicting Peritoneal Dialysis-Delivered Creatinine Clearance

Introduction: Measuring total (residual kidney plus peritoneal) creatinine clearance (CrCl) with 24-h urine and dialysate collections is recommended for peritoneal dialysis (PD) adequacy evaluation. Prediction equations applied in this instance could simplify the approach. Cockcroft-Gault and modification of diet in renal disease (MDRD) four (MDRD-4) and six (MDRD-6) variables equations have been tested in this setting, and conflicting results have been reported. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation is currently considered to be more sensitive than the established equations for kidney function estimation. However, its performance in PD adequacy evaluation has not been studied. Our aim was to assess CKD-EPI equation’s performance in predicting total measured CrCl (MCC) in PD patients. Material and methods: A group of 23 consecutive PD patients, male/female: 5/18, median age: 66 (32–91) years, median time on PD 32 (2–126) months, were enrolled in the study. All were treat...