Table 1. Comparison of CK-BB and AFP in 11 Patients

gestational age (at 14-36 weeks). We also saw no significant correlation between gestational age and CK-BB concentration; however, we did not look at amniotic fluid taken before the 14th week of gestation. In contrast to the findings of Poxall and Emery, we demonstrated increased CK-BB in the amniotic fluid of two women carrying anencephalic fetuses. We also found increased CK-BB in one caseof malignant sacrococcygeal teratoma, one case of gastroschisis, and one case of twins, possibly because the two infants were in one amniotic sack. Laboda and Britton (7) reported that the placenta is rich in CK-BB.Wefound no difference in CK-BB concentration between initial sample and fluid subsequently withdrawn in 10 selected amniotic fluids (data not shown) and therefore presume that the samples we