Disposition and Metabolism of Setipiprant, a Selective Oral CRTH2 Antagonist, in Humans
2013
Background
Setipiprant, a tetrahydropyridoindole derivative, is a CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper [Th]-2 cells) antagonist that has the potential to be effective in the treatment of patients with diseases with an allergic etiology, such as allergic rhinitis and asthma.
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