MoS2 quantum dots-combined zirconium-metalloporphyrin frameworks: Synergistic effect on electron transfer and application for bioassay

Abstract In this study, 2D-MoS 2 quantum dots (MQDs) were combined with the zirconium based porphyrinic metal-organic framework (MOF-545-Zn) through simple ultrasonic method for the purpose of the enhanced electrochemiluminescence (ECL). In addition, electrochemiluminescence (ECL), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were performed to investigate the synergistic effect on electron transfer of the composite. MQD loading with confined orientation on the surface of MOF-545-Zn was confirmed by morphology and spectroscopy. Moreover, from hybrids material, the higher ECL intensity was received. MOF-545-Zn@MQDs was functionalized by alpha lipoic acid (LA) and was further applied to develop a novel ECL immunosensors for carcinoembryonic antigen (CEA).