A Simple Approach to Nortropane and Nortrop-6-ene Derivatives.

Abstract Intramolecular cyclisation of trans -1-(benzylamino)-4-chlorocycloheptane and hept-2-ene gives the corresponding 8-azabicyclo[3.2.1]octane (nortropane) and -oct-6-ene (nortrop-6-ene) derivatives respectively. Under appropriate conditions, cyclohepta-1,3-diene is converted into nortropane in 75% overall yield.