Eradication of soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model by tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin.

11068Background: Soft-tissue sarcoma (STS) is a recalcitrant cancer with frequent failures after first-line therapy such as doxorubicin (DOX). More effective therapy and better mouse models to test...