Online Automatic Artifact Rejection using the Real-time EEG Source-mapping Toolbox (REST)

Non-brain contributions to electroencephalographic (EEG) signals, often referred to as artifacts, can hamper the analysis of scalp EEG recordings. This is especially true when artifacts have large amplitudes (e.g., movement artifacts), or occur continuously (like eye-movement artifacts). Offline automated pipelines can detect and reduce artifact in EEG data, but no good solution exists for online processing of EEG data in near real time. Here, we propose the combined use of online artifact subspace reconstruction (ASR) to remove large amplitude transients, and online recursive independent component analysis (ORICA) combined with an independent component (IC) classifier to compute, classify, and remove artifact ICs. We demonstrate the efficacy of the proposed pipeline using 2 EEG recordings containing series of (1) movement and muscle artifacts, and (2) cued blinks and saccades. This pipeline is freely available in the Real-time EEG Sourcemapping Toolbox (REST) for MATLAB (The Mathworks, Inc.).