Small complex prescription of traditional Chinese medicine for preventing and treating glucocorticoids-induced osteoporosis, and preparation method thereof

The invention provides a small complex prescription of a traditional Chinese medicine for preventing and treating glucocorticoids-induced osteoporosis, and a preparation method thereof. The complex prescription of the traditional Chinese medicine is composed of epimedium brevicornum maxim and ligustrum lucidum ait. Animal experiments demonstrate that the small complex prescription of the traditional Chinese medicine can effectively reduce the content of serum tartrate-resistant acid phosphatase and alkaline phosphatase, increase serum osteocalcin and the calcium content of bone tissues, and effectively improve pathological changes of the bone tissues, in a hormone-intervened wistar osteoporosis model. The small complex prescription of the traditional Chinese medicine is based on neutrally supplementing yin and yang in kidney with tonifying kidney and strengthening bones as treatment principles, can effectively prevent and alleviate adverse effects of osteoporosis caused by taking glucocorticoids for a long time, provide effective preparations for preventing and treating osteoporosis to other varieties of patients suffering from osteoporosis, and has good development and application prospects.