Molecular Mechanism of Acute Radiation Enteritis Revealed Using Proteomics and Biological Signaling Network Analysis in Rats

Background and Aims Radiation enteritis (RE) has emerged as a significant complication that can progress to severe gastrointestinal disease and the mechanisms underlying its genesis remain poorly understood. The aim of this study was to identify temporal changes in protein expression potentially associated with acute inflammation and to elucidate the mechanism underlying radiation enteritis genesis.