Cell Surface Localization of ABCG1 Does Not Require LXR Activation

In Response: Xie et al suggest that an alternative interpretation may explain the observation that LXR activation in macrophage preferentially presents ABCG1 at cell surface.1 They indicate that the newly synthesized ABCG1 on LXR activation may reach the cell surface through Golgi apparatus in macrophage, rather than via redistribution of preexisting ABCG1 from intracellular pools. Our interpretation that LXR activation facilitates redistribution of ABCG1 from an intracellular pool to …